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What is piriformis syndrome? Piriformis syndrome is a condition that affects both the muscles and the nerves in the buttock region. Specifically, piriformis syndrome occurs when the piriformis muscle, which is located deep in the buttock region, spasms and causes buttock pain. This may or may not irritate the sciatic nerve, which can create further
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What is piriformis syndrome, and how do you treat it? - Quora